Searchable abstracts of presentations at key conferences in endocrinology

ea0020me7 | (1) | ECE2009

Menopausal hormone therapy and cardiovascular disease: the women's health initiative (WHI) randomized placebo-controlled hormone trials

Stefanick Marcia

The Women’s Health Initiative (WHI) placebo-controlled trial of conjugated equine estrogens (CEE) plus medroxyprogesterone (MPA) in 16 608 postmenopausal women, aged 50–79 at randomization, was stopped after an average of 5.6 years of follow-up, due to increased risks, including increased coronary heart disease (CHD), stroke, and pulmonary embolism (PE), compared to health benefits. The WHI trial of CEE only in 10 739 women with prior hysterectomy, also aged 50–...